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Thyroid Hormone-Mediated Growth and Differentiation of Growth Plate Chondrocytes Involves IGF-1 Modulation of β-Catenin Signaling

Thyroid hormone regulates terminal differentiation of growth plate chondrocytes in part through modulation of the Wnt/β-catenin signaling pathway. Insulin-like growth factor 1 (IGF-1) has been described as a stabilizer of β-catenin, and thyroid hormone is a known stimulator of IGF-1 receptor express...

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Hlavní autoři: Wang, Lai, Shao, Yvonne Y, Ballock, R Tracy
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123724/
https://ncbi.nlm.nih.gov/pubmed/20200966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.5
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