Reduced Reelin Expression Accelerates Amyloid-β Plaque Formation and Tau Pathology in Transgenic Alzheimer's Disease Mice

In addition to the fundamental role of the extracellular glycoprotein Reelin in neuronal development and adult synaptic plasticity, alterations in Reelin-mediated signaling have been suggested to contribute to neuronal dysfunction associated with Alzheimer's disease (AD). In vitro data revealed...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Kocherhans, Samira, Madhusudan, Amrita, Doehner, Jana, Breu, Karin S., Nitsch, Roger M., Fritschy, Jean-Marc, Knuesel, Irene
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2010
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632461/
https://ncbi.nlm.nih.gov/pubmed/20610758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0418-10.2010
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