Repeated Mesenchymal Stem Cell Treatment after Neonatal Hypoxia–Ischemia Has Distinct Effects on Formation and Maturation of New Neurons and Oligodendrocytes Leading to Restoration of Damage, Corticospinal Motor Tract Activity, and Sensorimotor Function

Birth asphyxia is a frequent cause of perinatal morbidity and mortality with limited therapeutic options. We show that a single mesenchymal stem cell treatment at 3 d (MSC-3) after neonatal hypoxia–ischemia (HI) in postnatal day 9 mice improved sensorimotor function and reduced lesion size. A second...

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Publicado en:J Neurosci
Autores principales: van Velthoven, Cindy T. J., Kavelaars, Annemieke, van Bel, Frank, Heijnen, Cobi J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632441/
https://ncbi.nlm.nih.gov/pubmed/20631189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1835-10.2010
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