CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism

BACKGROUND: Mitochondrial oxidative phosphorylation (OXPHOS) via the respiratory chain is required for the maintenance of tumour cell proliferation and regulation of epithelial to mesenchymal transition (EMT)-related phenotypes through mechanisms that are not fully understood. The essential mitochon...

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Detalhes bibliográficos
Publicado no:Cancer Metab
Main Authors: Thomas, Luke W., Esposito, Cinzia, Stephen, Jenna M., Costa, Ana S. H., Frezza, Christian, Blacker, Thomas S., Szabadkai, Gyorgy, Ashcroft, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632184/
https://ncbi.nlm.nih.gov/pubmed/31346464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-019-0200-4
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