Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging

IMPORTANCE: Blood biomarkers able to diagnose Alzheimer disease (AD) at the preclinical stage would enable trial enrollment when the disease is potentially reversible. Plasma neuronal-enriched extracellular vesicles (nEVs) of patients with AD were reported to exhibit elevated levels of phosphorylate...

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Detalles Bibliográficos
Publicado en:JAMA Neurol
Autores principales: Kapogiannis, Dimitrios, Mustapic, Maja, Shardell, Michelle D., Berkowitz, Sean T., Diehl, Thomas C., Spangler, Ryan D., Tran, Joyce, Lazaropoulos, Michael P., Chawla, Sahil, Gulyani, Seema, Eitan, Erez, An, Yang, Huang, Chiung-Wei, Oh, Esther S., Lyketsos, Constantine G., Resnick, Susan M., Goetzl, Edward J., Ferrucci, Luigi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2019
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632160/
https://ncbi.nlm.nih.gov/pubmed/31305918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.2462
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