Extracellular vesicles reveal abnormalities in neuronal iron metabolism in restless legs syndrome

STUDY OBJECTIVES: Determine abnormalities in levels of iron-management proteins in neuronal origin-enriched extracellular vesicles (nEVs) in restless legs syndrome (RLS). METHODS: We used immunoprecipitation for neuronal marker L1CAM to isolate nEVs from the serum of 20 participants with RLS from a...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Chawla, Sahil, Gulyani, Seema, Allen, Richard P, Earley, Christopher J, Li, Xu, Van Zijl, Peter, Kapogiannis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Neurological Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612672/
https://ncbi.nlm.nih.gov/pubmed/30895312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsz079
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