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Alendronate-modified polymeric micelles for the treatment of breast cancer bone metastasis

Although the prognosis of patients with breast cancer continues to improve, breast cancer metastasis to bones remain high in incidence and challenging to manage. Here we report the development of bone-homing alendronate (ALN)-anchored biodegradable polymeric micelles for the targeted treatment of me...

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Dettagli Bibliografici
Pubblicato in:Mol Pharm
Autori principali: Liu, Tong, Romanova, Svetlana, Wang, Shuo, Hyun, Megan A., Zhang, Chi, Cohen, Samuel M., Singh, Rakesh K., Bronich, Tatiana K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632075/
https://ncbi.nlm.nih.gov/pubmed/31150251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01343
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