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Alendronate-modified polymeric micelles for the treatment of breast cancer bone metastasis

Although the prognosis of patients with breast cancer continues to improve, breast cancer metastasis to bones remain high in incidence and challenging to manage. Here we report the development of bone-homing alendronate (ALN)-anchored biodegradable polymeric micelles for the targeted treatment of me...

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Publicat a:Mol Pharm
Autors principals: Liu, Tong, Romanova, Svetlana, Wang, Shuo, Hyun, Megan A., Zhang, Chi, Cohen, Samuel M., Singh, Rakesh K., Bronich, Tatiana K.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632075/
https://ncbi.nlm.nih.gov/pubmed/31150251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01343
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