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Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms

BACKGROUND: At present, it is generally believed that leukemia stem cells are the source of AML, so the killing of leukemia stem cells has become important. Previous studies have suggested that HHT combined with ATO can synergistically kill U937 cells, and HHT has also demonstrated the ability to ki...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Tan, Ming, Zhang, Qian, Yuan, Xiaohong, Chen, Yuanzhong, Wu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631946/
https://ncbi.nlm.nih.gov/pubmed/31307525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1295-8
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