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Fabrication of Polymer Micelles with Zwitterionic Shell and Biodegradable Core for Reductively Responsive Release of Doxorubicin

To achieve a high stability in physiological environment and rapid intracellular drug release, a biodegradable zwitterionic triblock copolymer with a disulfide-linked poly-ε-caprolactone and polycarboxybetaine methacrylate (PCBMA-SS-PCL-SS-PCBMA) was prepared for micellar carrier to delivery doxorub...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Polymers (Basel)
Main Authors: Jiang, Junting, Li, Junbo, Zhou, Biyu, Niu, Chaohuang, Wang, Wendi, Wu, Wenlan, Liang, Ju
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631697/
https://ncbi.nlm.nih.gov/pubmed/31181866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym11061019
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