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Polymer Micelles with Cross-Linked Polyanion Core for Delivery of a Cationic Drug Doxorubicin

Polymer micelles with cross-linked ionic cores were prepared by using block ionomer complexes of poly(ethylene oxide)-b-poly(methacrylic acid) (PEO-b-PMA) copolymer and divalent metal cations as templates. Doxorubicin (DOX), an anthracycline anticancer drug, was successfully incorporated into the io...

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Detalles Bibliográficos
Main Authors: Kim, Jong Oh, Kabanov, Alexander V., Bronich, Tatiana K.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728168/
https://ncbi.nlm.nih.gov/pubmed/19386272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.04.019
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