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Recent Developments in Peptidyl Diaryl Phoshonates as Inhibitors and Activity-Based Probes for Serine Proteases

This review presents current achievements in peptidyl diaryl phosphonates as covalent, specific mechanism-based inhibitors of serine proteases. Along three decades diaryl phosphonates have emerged as invaluable tools in fundamental and applicative studies involving these hydrolases. Such an impact h...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Maślanka, Marta, Mucha, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631691/
https://ncbi.nlm.nih.gov/pubmed/31185654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12020086
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