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A click chemistry assay to identify natural product ligands for pre-microRNAs

Despite the great diversity of structure and function and relevance to human health, RNA remains an underexploited area of drug discovery. A major bottleneck toward this goal has been the identification of probes and drug leads that are specific for select RNAs and methods that will facilitate such...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods Enzymol
Hauptverfasser: Garner, Amanda L., Lorenz, Daniel A., Gallagher, Erin E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631307/
https://ncbi.nlm.nih.gov/pubmed/31239059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.04.020
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