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Insights into the Molecular Mechanisms of Eg5 Inhibition by (+)-Morelloflavone
(+)-Morelloflavone (MF) is an antitumor biflavonoid that is found in the Garcinia species. Recently, we reported MF as a novel inhibitor of ATPase and microtubules-gliding activities of the kinesin spindle protein (Eg5) in vitro. Herein, we provide dynamical insights into the inhibitory mechanisms o...
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| Publicado no: | Pharmaceuticals (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6630617/ https://ncbi.nlm.nih.gov/pubmed/30995725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12020058 |
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