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CHAPTER X: A HYBRID APPROACH FOR PROTEIN STRUCTURE DETERMINATION COMBINING SPARSE NMR WITH EVOLUTIONARY COUPLING SEQUENCE DATA

While 3D structure determination of small (<15 kDa) proteins by solution NMR is largely automated and routine, structural analysis of larger proteins is more challenging. An emerging hybrid strategy for modeling protein structures combines sparse NMR data that can be obtained for larger proteins...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Huang, Yuanpeng Janet, Brock, Kelly, Sander, Chris, Marks, Debora S., Montelione, Gaetano T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630173/
https://ncbi.nlm.nih.gov/pubmed/30617828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-13-2200-6_10
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