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CHAPTER X: A HYBRID APPROACH FOR PROTEIN STRUCTURE DETERMINATION COMBINING SPARSE NMR WITH EVOLUTIONARY COUPLING SEQUENCE DATA

While 3D structure determination of small (<15 kDa) proteins by solution NMR is largely automated and routine, structural analysis of larger proteins is more challenging. An emerging hybrid strategy for modeling protein structures combines sparse NMR data that can be obtained for larger proteins...

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Bibliographische Detailangaben
Veröffentlicht in:Adv Exp Med Biol
Hauptverfasser: Huang, Yuanpeng Janet, Brock, Kelly, Sander, Chris, Marks, Debora S., Montelione, Gaetano T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630173/
https://ncbi.nlm.nih.gov/pubmed/30617828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-13-2200-6_10
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