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Effect of genetic background on the cardiac phenotype in a mouse model of Emery-Dreifuss muscular dystrophy
A-type lamins gene (LMNA) mutations cause an autosomal dominant inherited form of Emery-Dreifuss muscular dystrophy (EDMD). EDMD is characterized by slowly progressive muscle weakness and wasting and dilated cardiomyopathy, often leading to heart failure-related disability. EDMD is highly penetrant...
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| Publicado no: | Biochem Biophys Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6630059/ https://ncbi.nlm.nih.gov/pubmed/31341969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100664 |
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