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BK channel clustering is required for normal behavioral alcohol sensitivity in C. elegans

The large conductance, calcium- and voltage-activated potassium channel, known as the BK channel, is one of the central proteins that mediate alcohol intoxication and tolerance across species. Although ethanol targets BK channels through direct interaction, how ethanol-mediated BK channel activation...

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Pubblicato in:Sci Rep
Autori principali: Oh, Kelly H., Kim, Hongkyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629859/
https://ncbi.nlm.nih.gov/pubmed/31308408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46615-9
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