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Sleeping Beauty Mouse Models of Cancer: Microenvironmental Influences on Cancer Genetics

The Sleeping Beauty (SB) transposon insertional mutagenesis system offers a streamlined approach to identify genetic drivers of cancer. With a relatively random insertion profile, SB is uniquely positioned for conducting unbiased forward genetic screens. Indeed, SB mouse models of cancer have reveal...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Guimaraes-Young, Amy, Feddersen, Charlotte R., Dupuy, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629774/
https://ncbi.nlm.nih.gov/pubmed/31338332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00611
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