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Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring

Exposure to maternal diabetes during pregnancy results in diabetes in offspring, but its underlying mechanisms are unclear. Here, we investigated the phenotype and molecular defects of the offspring of poorly controlled diabetic female mice generated by streptozotocin (STZ) administration. Offspring...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Inoguchi, Yukihiro, Ichiyanagi, Kenji, Ohishi, Hiroaki, Maeda, Yasutaka, Sonoda, Noriyuki, Ogawa, Yoshihiro, Inoguchi, Toyoshi, Sasaki, Hiroyuki
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629688/
https://ncbi.nlm.nih.gov/pubmed/31308441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46638-2
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