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Apoptotic signalling targets the post-endocytic sorting machinery of the death receptor Fas/CD95

Fas plays a major role in regulating ligand-induced apoptosis in many cell types. It is well known that several cancers demonstrate reduced cell surface levels of Fas and thus escape a potential control system via ligand-induced apoptosis, although underlying mechanisms are unclear. Here we report t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sharma, Shruti, Carmona, Antonio, Skowronek, Agnieszka, Yu, Fangyan, Collins, Mark O., Naik, Sindhu, Murzeau, Claire M., Tseng, Pei-Li, Erdmann, Kai S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629679/
https://ncbi.nlm.nih.gov/pubmed/31308371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11025-y
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