Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence

BACKGROUND: Sphingolipids (SPs) are ubiquitous, structurally diverse molecules that include ceramides, sphingomyelins (SMs), and sphingosines. They are involved in various pathologies, including obesity and type 2 diabetes mellitus (T2DM). Therefore, it is likely that perturbations in plasma concent...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Chew, Wee Siong, Torta, Federico, Ji, Shanshan, Choi, Hyungwon, Begum, Husna, Sim, Xueling, Khoo, Chin Meng, Khoo, Eric Yin Hao, Ong, Wei-Yi, Van Dam, Rob M., Wenk, Markus R., Tai, E. Shyong, Herr, Deron R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Clinical Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629294/
https://ncbi.nlm.nih.gov/pubmed/31162145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126925
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