Characterization of pathogenic monoclonal autoantibodies derived from muscle-specific kinase myasthenia gravis patients

Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by muscle weakness and caused by pathogenic autoantibodies that bind to membrane proteins at the neuromuscular junction. Most patients have autoantibodies against the acetylcholine receptor (AChR), but a subset of patients have au...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Takata, Kazushiro, Stathopoulos, Panos, Cao, Michelangelo, Mané-Damas, Marina, Fichtner, Miriam L., Benotti, Erik S., Jacobson, Leslie, Waters, Patrick, Irani, Sarosh R., Martinez-Martinez, Pilar, Beeson, David, Losen, Mario, Vincent, Angela, Nowak, Richard J., O’Connor, Kevin C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629167/
https://ncbi.nlm.nih.gov/pubmed/31217355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127167
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