Characterization of pathogenic monoclonal autoantibodies derived from muscle-specific kinase myasthenia gravis patients

Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by muscle weakness and caused by pathogenic autoantibodies that bind to membrane proteins at the neuromuscular junction. Most patients have autoantibodies against the acetylcholine receptor (AChR), but a subset of patients have au...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Takata, Kazushiro, Stathopoulos, Panos, Cao, Michelangelo, Mané-Damas, Marina, Fichtner, Miriam L., Benotti, Erik S., Jacobson, Leslie, Waters, Patrick, Irani, Sarosh R., Martinez-Martinez, Pilar, Beeson, David, Losen, Mario, Vincent, Angela, Nowak, Richard J., O’Connor, Kevin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629167/
https://ncbi.nlm.nih.gov/pubmed/31217355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127167
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