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Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver
Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent, and potentially morbid, disease that affects one-third of the US population. Normal liver safely accommodates lipid excess during fasting or carbohydrate restriction by increasing their oxidation to acetyl-CoA and ketones, yet lipid exc...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629163/ https://ncbi.nlm.nih.gov/pubmed/31012869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127737 |
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