Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction

Despite the accepted notion that granulocytes play a universally destructive role in organ and tissue grafts, it has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. The mechanism of eosinophil-mediated tolerance, or their role...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Onyema, Oscar Okwudiri, Guo, Yizhan, Mahgoub, Bayan, Wang, Qing, Manafi, Amir, Mei, Zhongcheng, Banerjee, Anirban, Li, Dongge, Stoler, Mark H., Zaidi, Melissa T., Schrum, Adam G., Kreisel, Daniel, Gelman, Andrew E., Jacobsen, Elizabeth A., Krupnick, Alexander Sasha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629120/
https://ncbi.nlm.nih.gov/pubmed/31167966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128241
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