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Critical role of IL-21 and T follicular helper cells in hypertension and vascular dysfunction

T and B cells have been implicated in hypertension, but the mechanisms by which they produce a coordinated response is unknown. T follicular helper (Tfh) cells that produce IL-21 promote germinal center (GC) B cell responses, leading to Ig production. Here we investigate the role of IL-21 and Tfh ce...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JCI Insight
मुख्य लेखकों: Dale, Bethany L., Pandey, Arvind K., Chen, Yuhan, Smart, Charles D., Laroumanie, Fanny, Ao, Mingfang, Xiao, Liang, Dikalova, Anna E., Dikalov, Sergey I., Elijovich, Fernando, Foss, Jason D., Barbaro, Natalia R., Van Beusecum, Justin P., Deger, Serpil M., Alsouqi, Aseel, Itani, Hana A., Norlander, Allison E., Alexander, Matthew R., Zhao, Shilin, Ikizler, T. Alp, Algood, Holly M. Scott, Madhur, Meena S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629096/
https://ncbi.nlm.nih.gov/pubmed/31013256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129278
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