लोड हो रहा है...
Dual muscle-liver transduction imposes immune tolerance for muscle transgene engraftment despite preexisting immunity
Immune responses to therapeutic transgenes are a potential hurdle to treat monogenic muscle disorders. These responses result from the neutralizing activity of transgene-specific B cells and cytotoxic T cells recruited upon gene transfer. We explored here how dual muscle-liver expression of a foreig...
में बचाया:
| में प्रकाशित: | JCI Insight |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Clinical Investigation
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629094/ https://ncbi.nlm.nih.gov/pubmed/31167976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127008 |
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