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A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass
Cellular senescence is an important mechanism of autonomous tumor suppression, while its consequence such as the senescence-associated secretory phenotype (SASP) may drive tumorigenesis and age-related diseases. Therefore, controlling the cell fate optimally when encountering senescence stress is he...
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| Опубликовано в: : | Aging (Albany NY) |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628988/ https://ncbi.nlm.nih.gov/pubmed/31219803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102034 |
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