A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass

Cellular senescence is an important mechanism of autonomous tumor suppression, while its consequence such as the senescence-associated secretory phenotype (SASP) may drive tumorigenesis and age-related diseases. Therefore, controlling the cell fate optimally when encountering senescence stress is he...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging (Albany NY)
Prif Awduron: Liu, Xuehui, Wei, Lei, Dong, Qiongye, Liu, Liyang, Zhang, Michael Q., Xie, Zhen, Wang, Xiaowo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628988/
https://ncbi.nlm.nih.gov/pubmed/31219803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102034
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