Concurrent Exposure of Neutralizing and Non-neutralizing Epitopes on a Single HIV-1 Envelope Structure

The trimeric envelope spikes on the HIV-1 virus surface initiate infection and comprise key targets for antiviral humoral responses. Circulating virions variably present intact envelope spikes, which react with neutralizing antibodies; and altered envelope structures, which bind non-neutralizing ant...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Ray, Krishanu, Mengistu, Meron, Orlandi, Chiara, Pazgier, Marzena, Lewis, George K., DeVico, Anthony L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628914/
https://ncbi.nlm.nih.gov/pubmed/31338095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01512
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