An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress

Emerin is a nuclear envelope protein that contributes to genome organization and cell mechanics. Through its N-terminal LAP2-emerin-MAN1 (LEM)-domain, emerin interacts with the DNA-binding protein barrier-to-autointegration (BAF). Emerin also binds to members of the linker of the nucleoskeleton and...

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Published in:Cells
Main Authors: Essawy, Nada, Samson, Camille, Petitalot, Ambre, Moog, Sophie, Bigot, Anne, Herrada, Isaline, Marcelot, Agathe, Arteni, Ana-Andreea, Coirault, Catherine, Zinn-Justin, Sophie
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628311/
https://ncbi.nlm.nih.gov/pubmed/31185657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060570
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