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Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases

Lamins are the main components of the nucleoskeleton. Whereas their 3D organization was recently described using cryoelectron tomography, no structural data highlights how they interact with their partners at the interface between the inner nuclear envelope and chromatin. A large number of mutations...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Samson, Camille, Petitalot, Ambre, Celli, Florian, Herrada, Isaline, Ropars, Virginie, Le Du, Marie-Hélène, Nhiri, Naïma, Jacquet, Eric, Arteni, Ana-Andrea, Buendia, Brigitte, Zinn-Justin, Sophie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212729/
https://ncbi.nlm.nih.gov/pubmed/30137533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky736
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