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Targeted Therapy of Uveal Melanoma: Recent Failures and New Perspectives
Among Uveal Melanoma (UM) driver mutations, those involving GNAQ or GNA11 genes are the most frequent, while a minor fraction of tumors bears mutations in the PLCB4 or CYSLTR2 genes. Direct inhibition of constitutively active oncoproteins deriving from these mutations is still in its infancy in UM,...
Gardado en:
| Publicado en: | Cancers (Basel) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628160/ https://ncbi.nlm.nih.gov/pubmed/31216772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060846 |
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