Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway

Background: Colorectal cancer (CRC) is one of the most prevalent gastrointestinal malignancies. The incidence of CRC has been rapidly increasing in China. Transferrin receptor 1 (TfR1) is a key regulator of cellular iron homeostasis. Several studies have demonstrated TfR1 overexpression in a variety...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Manag Res
Auteurs principaux: Cui, Can, Cheng, Xiaojing, Yan, Liang, Ding, Huirong, Guan, Xiaoya, Zhang, Wenlong, Tian, Xiuyun, Hao, Chunyi
Format: Artigo
Langue:Inglês
Publié: Dove 2019
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628123/
https://ncbi.nlm.nih.gov/pubmed/31372038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S198911
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