Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-β/Smads Pathway

Slit2 (slit guidance ligand 2), a ligand of the Roundabout1 (Robo1) transmembrane receptor, is often overexpressed in colorectal carcinomas (CRCs). In this study, we performed data mining in the Metabolic gEne RApid Visualizer (MERAV) database and found that Slit2 and TGF-β1 (Transforming growth fac...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Yao, Yuying, Zhou, Zijun, Li, Liuyou, Li, Junchen, Huang, Lixun, Li, Jiangchao, Qi, Cuiling, Zheng, Lingyun, Wang, Lijing, Zhang, Qian-Qian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628122/
https://ncbi.nlm.nih.gov/pubmed/31242633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060635
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