Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index Than Sorafenib via Zebrafish Drug Screening Platform

Hepatocellular carcinoma (HCC) ranks as the fourth leading cause of cancer-related deaths worldwide. Sorafenib was the only U.S. Food and Drug Administration (FDA) approved drug for treating advanced HCC until recently, so development of new target therapy is urgently needed. In this study, we estab...

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Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Lin, Han-Syuan, Huang, Yi-Luen, Wang, Yi-Rui Stefanie, Hsiao, Eugene, Hsu, Tsu-An, Shiao, Hui-Yi, Jiaang, Weir-Torn, Sampurna, Bonifasius Putera, Lin, Kuan-Hao, Wu, Ming-Shun, Lai, Gi-Ming, Yuh, Chiou-Hwa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628114/
https://ncbi.nlm.nih.gov/pubmed/31141996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060739
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