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Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling

BACKGROUND: Hepatocellular carcinoma ranks fourth in cancer‐related mortality currently lacks effective therapeutics. Fucoidan is sulfated polysaccharide that is mainly found in brown seaweeds. In this study, we investigated the effects and mechanisms of low molecular weight fucoidan (i.e. oligo‐fuc...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Wu, Szu‐Yuan, Yang, Wan‐Yu, Cheng, Chun‐Chia, Lin, Kuan‐Hao, Sampurna, Bonifasius Putera, Chan, Suat‐Ming, Yuh, Chiou‐Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752165/
https://ncbi.nlm.nih.gov/pubmed/33377648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.252
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