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NOS2 inhibitor 1400W Induces Autophagic Flux and Influences Extracellular Vesicle Profile in Human Glioblastoma U87MG Cell Line

The relevance of nitric oxide synthase 2 (NOS2) as a prognostic factor in Glioblastoma Multiforme (GBM) malignancy is emerging. We analyzed the effect of NOS2 inhibitor 1400W on the autophagic flux and extracellular vesicle (EV) secretion in U87MG glioma cells. The effects of glioma stem cells (GSC)...

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Publicat a:Int J Mol Sci
Autors principals: Palumbo, Paola, Lombardi, Francesca, Augello, Francesca Rosaria, Giusti, Ilaria, Luzzi, Sabino, Dolo, Vincenza, Cifone, Maria Grazia, Cinque, Benedetta
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627770/
https://ncbi.nlm.nih.gov/pubmed/31226744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123010
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