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Biological effects of selective COX-2 inhibitor NS398 on human glioblastoma cell lines

BACKGROUND: Cyclooxygenase-2 (COX-2), an inflammation-associated enzyme, has been implicated in tumorigenesis and progression of glioblastoma (GBM). The poor survival of GBM was mainly associated with the presence of glioma stem cells (GSC) and the markedly inflammatory microenvironment. To further...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Palumbo, Paola, Lombardi, Francesca, Augello, Francesca Rosaria, Giusti, Ilaria, Dolo, Vincenza, Leocata, Pietro, Cifone, Maria Grazia, Cinque, Benedetta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222447/
https://ncbi.nlm.nih.gov/pubmed/32435158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01250-7
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