Melanopsin(+)RGCs Are fully Resistant to NMDA-Induced Excitotoxicity

We studied short- and long-term effects of intravitreal injection of N-methyl-d-aspartate (NMDA) on melanopsin-containing (m(+)) and non-melanopsin-containing (Brn3a(+)) retinal ganglion cells (RGCs). In adult SD-rats, the left eye received a single intravitreal injection of 5µL of 100nM NMDA. At 3...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Vidal-Villegas, Beatriz, Di Pierdomenico, Johnny, Miralles de Imperial-Ollero, Juan A, Ortín-Martínez, Arturo, Nadal-Nicolás, Francisco M, Bernal-Garro, Jose M, Cuenca Navarro, Nicolás, Villegas-Pérez, María P, Vidal-Sanz, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627747/
https://ncbi.nlm.nih.gov/pubmed/31226772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123012
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