Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo

Here, we evaluated the effects of PEDF (pigment epithelium-derived factor) and PEDF peptides on cone-photoreceptor cell damage in a mouse model of focal LED-induced phototoxicity (LIP) in vivo. Swiss mice were dark-adapted overnight, anesthetized, and their left eyes were exposed to a blue LED place...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Valiente-Soriano, Francisco J., Di Pierdomenico, Johnny, García-Ayuso, Diego, Ortín-Martínez, Arturo, Miralles de Imperial-Ollero, Juan A., Gallego-Ortega, Alejandro, Jiménez-López, Manuel, Villegas-Pérez, M. Paz, Becerra, S. Patricia, Vidal-Sanz, Manuel
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582775/
https://ncbi.nlm.nih.gov/pubmed/33008127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197242
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