Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to standard chemo- and radiotherapy. Recently, a new class of non-platinum-based halogenated molecules (called FMD compounds) was discovered that selectively kills cancer cells. Here, we investigate the potential of 1,2-Diamino-...

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Udgivet i:Cells
Main Authors: Goetze, Robert G., Buchholz, Soeren M., Ou, Ning, Zhang, Qinrong, Patil, Shilpa, Schirmer, Markus, Singh, Shiv K., Ellenrieder, Volker, Hessmann, Elisabeth, Lu, Qing-Bin, Neesse, Albrecht
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627568/
https://ncbi.nlm.nih.gov/pubmed/31181844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060563
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