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Genome-Wide Profiling of Laron Syndrome Patients Identifies Novel Cancer Protection Pathways

Laron syndrome (LS), or primary growth hormone resistance, is a prototypical congenital insulin-like growth factor 1 (IGF1) deficiency. The recent epidemiological finding that LS patients do not develop cancer is of major scientific and clinical relevance. Epidemiological data suggest that congenita...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Werner, Haim, Lapkina-Gendler, Lena, Achlaug, Laris, Nagaraj, Karthik, Somri, Lina, Yaron-Saminsky, Danielle, Pasmanik-Chor, Metsada, Sarfstein, Rive, Laron, Zvi, Yakar, Shoshana
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627189/
https://ncbi.nlm.nih.gov/pubmed/31208077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060596
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