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Mycolactone Toxin Membrane Permeation: Atomistic versus Coarse-Grained MARTINI Simulations
Mycolactone, a cytotoxic and immunosuppressive macrolide produced by Mycobacterium ulcerans, is the central virulent factor in the skin disease Buruli ulcer. This multifunctional cytotoxin affects fundamental cellular processes such as cell adhesion, immune response, and cell death by targeting vari...
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| Publicado en: | Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626831/ https://ncbi.nlm.nih.gov/pubmed/31174850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.05.012 |
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