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Effects of Chronic Cocaine Self-Administration and N-acetylcysteine on Learning, Cognitive Flexibility, and Reinstatement in Nonhuman Primates

RATIONALE. Cocaine use disorder (CUD) is associated with cognitive deficits that have been linked to poor treatment outcomes. An improved understanding of cocaine’s deleterious effects on cognition may help optimize pharmacotherapies. Emerging evidence implicates abnormalities in glutamate neurotran...

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Détails bibliographiques
Publié dans:Psychopharmacology (Berl)
Auteurs principaux: Kangas, Brian D., Doyle, Rachel J., Kohut, Stephen J., Bergman, Jack, Kaufman, Marc J.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626691/
https://ncbi.nlm.nih.gov/pubmed/30877326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-019-05211-5
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