Effects of Chronic Cocaine Self-Administration and N-acetylcysteine on Learning, Cognitive Flexibility, and Reinstatement in Nonhuman Primates

RATIONALE. Cocaine use disorder (CUD) is associated with cognitive deficits that have been linked to poor treatment outcomes. An improved understanding of cocaine’s deleterious effects on cognition may help optimize pharmacotherapies. Emerging evidence implicates abnormalities in glutamate neurotran...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: Kangas, Brian D., Doyle, Rachel J., Kohut, Stephen J., Bergman, Jack, Kaufman, Marc J.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626691/
https://ncbi.nlm.nih.gov/pubmed/30877326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-019-05211-5
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