Llwytho...
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity
MICA and MICB are expressed by many human cancers as a result of cellular stress, and can tag cells for elimination by cytotoxic lymphocytes through natural killer group 2D (NKG2D) receptor activation. However, tumors evade this immune recognition pathway through proteolytic shedding of MICA and MIC...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Science |
|---|---|
| Prif Awduron: | , , , , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626532/ https://ncbi.nlm.nih.gov/pubmed/29599246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao0505 |
| Tagiau: |
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