Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes

BACKGROUND: Type 1 diabetes mellitus (T1DM) patients display increased risk of cardiovascular disease (CVD) and are characterized by a diminished regulatory T (Treg) cell content or function. Previous studies have shown an association between decreased CDKN2A/2B/2BAS gene expression and enhanced CVD...

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Publicat a:J Transl Med
Autors principals: Martínez-Hervás, Sergio, Sánchez-García, Verónica, Herrero-Cervera, Andrea, Vinué, Ángela, Real, José Tomás, Ascaso, Juan F., Burks, Deborah Jane, González-Navarro, Herminia
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626385/
https://ncbi.nlm.nih.gov/pubmed/31299986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1977-1
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