Molecular Genetics and Functional Analysis Implicate CDKN2BAS1-CDKN2B Involvement in POAG Pathogenesis

The genes in the 9p21 locus (CDKN2B-AS1 & CDKN2B) are widely associated with Primary open-angle glaucoma (POAG). However, the functional importance of this locus in POAG pathogenesis is still unexplored. This study investigated the role of CDKN2BAS1-CDKN2B axis in POAG. We observed significant a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Rathi, Sonika, Danford, Ian, Gudiseva, Harini V., Verkuil, Lana, Pistilli, Maxwell, Vishwakarma, Sushma, Kaur, Inderjeet, Dave, Tarjani Vivek, O’Brien, Joan M., Chavali, Venkata R. M.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564117/
https://ncbi.nlm.nih.gov/pubmed/32825664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091934
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